Can fibroblasts determine the late differing outcome between systemic sclerosis and primary hypertrophic osteoarthropathy (pachydermoperiostosis)?
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چکیده
منابع مشابه
Pachydermoperiostosis (Primary Hypertrophic Osteoarthropathy): Case Report
syndrome consisting of clubbing of the digits of the hands and feet, enlargement of the extremities secondary to periarticular and osseous proliferation, and painful and swollen joints. The condition has been divided into two categories, primary hypertrophic osteoarthropathy, also known as “pachydermoperiostosis”, and secondary hypertrophic osteoarthropathy, frequently referred to as “hypertrop...
متن کاملPachydermoperiostosis (primary hypertrophic osteoarthropathy): report of a case with evidence of endothelial and connective tissue involvement.
A case of pachydermoperiostosis characterised by the presence of finger clubbing, periostosis, sweating of hands and feet is described. Modifications of capillaroscopic pattern and of arteriovenous anastomoses are reported. The periungual border and finger tip tissue showed diffuse endothelial hyperplasia, hyalinosis, and sclerosis with packing of collagen fibres. Electron microscopy showed hyp...
متن کاملHypertrophy of the feet and ankles presenting in primary hypertrophic osteoarthropathy or pachydermoperiostosis: a case report
INTRODUCTION Pachydermoperiostosis or primary hypertrophic osteoathropathy is a rare genetic disease with autosomal transmission. This disorder, which affects both bones and skin, is characterized by the association of dermatologic changes (pachydermia or thickening of the skin) and rheumatologic manifestations (periostosis and finger clubbing). Here, we report a new observation of pachydermope...
متن کاملPachydermoperiostosis vs. Acromegaly in a Patient with Cutis Verticis Gyrata
We discuss a complicated case of a 34 year-old male with cutis verticis gyrata presenting simultaneously with hypertrophic osteoarthropathy and a pituitary macroadenoma. The patient was initially suspected of having acromegaly secondary to the pituitary adenoma but further workup showed normal insulin growth factor-1 and growth hormone levels inconsistent with acromegaly. Subsequent workup was ...
متن کاملPachydermoperiostosis in a patient with chronic hepatitis B virus infection referred as acromegaly: a case report
BACKGROUND Primary hypertrophic osteoarthropathy also known as pachydermoperiostosis is a rare genetic disorder that has often been confused with acromegaly because of similar clinical features. Vascular endothelial growth factors which have been implicated in the clinical features of pachydermoperiostosis, have also been shown to be present in chronic hepatitis and implicated in the malignant ...
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ورودعنوان ژورنال:
- Clinical and experimental rheumatology
دوره 18 1 شماره
صفحات -
تاریخ انتشار 2000